Lot's father, Abraham's brother died in Ur before Abraham left at God's direction. The Bible does not say why Abraham chose to leave with Lot, we can deduce that he probably felt a sense of responsibility towards his nephew and felt he would be better of going with him than staying with his aging grand father. Lot followed Abraham and Sarah to Canaan, then to Egypt and back to Canaan.
Going with Abraham was the best decision Lot made, for as God blessed and prospered Abraham, Lot became blessed and prosperous also. The two men prospered so much that the land where they settled became too small to contain both Abraham's and Lot's possessions. "Now the land was not able to support them, that they might dwell together, for their possessions were so great that they could not dwell together" Genesis 13:6. Lot's herdsman begun to quarrel with Abraham's and things started getting pretty uncomfortable.
At that point Abraham realized it was time to cut Lot loose. Their association with each other was starting to do more harm than good. The patriarch realized that if care was not taken, the relationship could be ruined for good. "So Abram said to Lot, “please let there be no strife between you and me, and between my herdsmen and your herdsmen; for we are brethren." Genesis 13:8. With that the two men parted ways.
Sometimes we keep people in our lives longer than we need to. Sometimes we allow people who were just supposed to pass through our lives to become permanent residents. Not everyone who comes into your life is suppose to play a key role in your story. Do not allow an extra to become your sidekick. Know when people's time is up and cut them loose. Know when parting ways is more of a blessing than a disaster. Some have overstayed their welcome in your life and are reeking havoc on you; cut them loose.
As soon as Abraham realized the land was too small to contain both of them and their possessions and servants, and that the servants from both sides had started quarreling, he knew IT WAS TIME.
There are always indicators for when it is time. When someone in your life sees nothing good in you; has nothing good to say to you or about you; always finds a problem for every solution you find; never applauds you on any achievement; never puts you first; always takes from you and never gives; never encourages but quick to criticize, etc, then you know it is time. Their presence in your life is causing more harm than good. You do not need them.
May God give us the wisdom to cast off the excess weights that slow us down in our journey to fulfill purpose and live to our fullest potential.